职业经历

Dr. Lodge 是一名细胞生物学家，在学术研究领域具有广泛的经验，初期从事制药及干细胞疗法监管事务。博士和博士后就读阶段，他主要研究神经系统发育过程中肌动蛋白细胞骨架和细胞黏附分子对轴突导向的作用。Dr. Lodge 于2001年加入葛兰素史克 (GlaxoSmithKline) 公司，领导神经变性疾病和精神疾病的目标识别和确认工作，以及干细胞相关的药物研发战略的开发。2009年至2011年间，Dr Lodge任伦敦大学学院 (University College London) 干细胞疗法项目负责人，负责根据最新颁布的高级治疗要用产品(ATMPs)指令申请相关证照的工作。他具有广泛的细胞生物、分子生物和蛋白质生化技术等方面的专业技能，在国际同行评审期刊上发表过多篇第一作者文章，对于多种临床前及临床规范性文件的写作经验丰富。Dr. Lodge 目前从事基于细胞的药物研究、ATMP监管事务以及学术写作(包括web开发)方面的咨询工作，从2008年起开始为 Edanz Group 工作。

Dr Lodge is a cell biologist with wide-ranging experience in academic research, early stage drug discovery, and stem cell therapy regulatory affairs. For his PhD and postdoctoral work, Dr Lodge studied the roles of the actin cytoskeleton and cell adhesion molecules in axon guidance during nervous system development. Dr Lodge joined GlaxoSmithKline in 2001, where he held research and programme leadership roles within target validation initiatives for neurodegenerative and psychiatric diseases. He was also involved in developing drug discovery strategies involving stem cells. From 2009 to 2011, Dr Lodge was Programme Manager for a stem cell therapy unit at University College London, where he was responsible for the unit obtaining the necessary licenses required by the recently introduced Advanced Therapy Medicinal Products (ATMPs) directive. His technical expertise covers a broad spectrum of cell biology, molecular biology and protein biochemistry techniques, including their application to drug discovery assay development. Dr Lodge has published several first author publications in international peer-reviewed journals, and he is experienced in writing a variety of pre-clinical and clinical regulatory documents. Dr Lodge currently offers consulting services in cell-based drug discovery, ATMP regulatory affairs, and scientific writing (including web development). He began editing for the Edanz Group in 2008.

职业经历

Dr. Thompson 主要致力于肾生理学/内分泌学、糖尿病和生殖学领域的科学研究。在博士研究阶段，她深入探究了类固醇代谢对肾功能的影响，并通过博士后阶段进一步研究了各种系统(包括人类胎盘和糖尿病模型鼠)中的类固醇代谢。她还研究了葡萄糖毒性对糖尿病动物模型细胞内信号传导的影响。研究技能包括：类固醇放射免疫试验，组织学，mRNA/DNA 提取和纯化，RT-PCR， 原位 RT-PCR，原代细胞培养，DNA 纯化、复制及足迹法，Northern、Southern 和 Western 免疫印迹，光学/荧光/共焦显微法等。Dr. Thompson 具有出色的写作技巧，著有大量的同行评审期刊文章，从事了五年的全职医学作者工作，写作范围涉及糖尿病学、胃肠病学、免疫学、肿瘤学和哮喘等众多领域。Dr. Thompson 从 2008 年起开始为 Edanz Editing 工作。

Dr. Thompson's scientific background is in physiology with an emphasis on renal physiology/endocrinology, diabetes and reproduction. For her PhD she investigated the effects of steroid metabolism on renal function and as a Postdoctoral Fellow she focused on steroid metabolism in various systems including human placenta and diabetic mice models. She also investigated the impact of glucose toxicity on intracellular signaling in diabetic animal models. Technical skills include steroid radio-immunoassay, histology, mRNA/DNA extraction and purification, RT-PCR, in situ RT-PCR, primary cell culture, DNA purification, cloning and footprinting, Northern, Southern and Western blots and light/fluorescence/confocal microscopy. Dr. Thompson has excellent writing skills and has written numerous peer-reviewed journal articles. She has over 5 years’ experience as a full-time Medical Writer in a wide range of topics including diabetes, gastroenterology, immunology, oncology and asthma. Dr Thompson began working with Edanz Editing in 2008.